Summary
CASE REPORTS
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Extract
The incidence of recurrent herpes simplex and herpes zoster infection during treatment with arsenic trioxide.
Abstract
We report the incidence of varicella zoster virus (VZV) and herpes simplex virus (HSV) infection in patients with multiple myeloma and colon cancer who were treated with arsenic trioxide for their disease. In this report, we discuss the effects of arsenic on immune system, and suggest arsenic compounds as a possible predisposing factor for viral reactivation in these patients. Introduction Historically, formulations of arsenic have been used in medicine for over 2,400 years. (1) Inorganic arsenic compounds such as Fowler's solution and Pearson's solution have been used in the treatment of asthma and psoriasis, while organic arsenic compounds have had a widespread use ...See the full content of this document
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