The safety and efficacy of fractional photothermolysis for the correction of striae distensae.

Journal of Drugs in DermatologyVol. 7 Nbr. 9, September 2008

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The safety and efficacy of fractional photothermolysis for the correction of striae distensae.

ABSTRACT

Background: Improving the appearance of striae distensae, particularly striae alba, has remained a challenge due to the limited availability of effective and low-risk treatment options. Fractional photothermolysis, a novel concept in skin rejuvenation, has been reported to be effective in the treatment of facial rhytides, acne scars, and surgical scars, but its use in the treatment of striae has not been well studied.

Objective: To determine the safety and efficacy of fractional photothermolysis treatment on striae alba and striae rubra.

Methods: Twenty female patients with striae rubra or striae alba on their abdomen, thighs, or buttocks were enrolled in the study. Lesions were randomized to receive treatment, with site-matched normal control areas. Patients received a total of 6 treatments using a 1550-nm, erbium-doped fiber laser with 2 to 3 weeks of elapsed time between treatments. Clinical response to treatment was assessed at each visit, and at 1-month, 2-month, and 3-month follow-up intervals by the patient and investigator. A comparison evaluation of 8 pati...

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