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Exercise performance and muscle contractile properties after creatine monohydrate supplementation in aerobic-anaerobic training rats.
Abstract
The purpose of this study was to investigate the effects of creatine monohydrate supplementation on exercise performance and contractile variables in aerobic-anaerobic training rats. Twenty 90-day-old male Sprague Dawley rats were divided into two groups--creatine (Cr) and controls (K). The creatine group received creatine monohydrate as a nutritional supplement, whereas the control group was given placebo. Both groups were trained 5 days a week on a treadmill for 20 days in a mixed (aerobic-anaerobic) metabolic working regimen (27 m.[min.sup.-1], 15% elevation for 40 min). The exercise performance (sprint-test), contractile properties (m. tibialis anterior), oxidative enzyme activity (SDH, LDH, NADH2) in m. soleus and blood hematological and chemical variables were assessed in the groups at the end of the experiment. It was found out that creatine supplementation improved the exercise performance after 20 days of administration in a dose of 60 mg per day on the background of a mixed (aerobic-anaerobic) exercise training. At the end of the trial the Cr-group demonstrated better values for the variables which characterize the contractile ...See the full content of this document
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