Computing Gene Regulation

Scientist, TheJuly 30, 2009

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Computing Gene Regulation

Eukaryotic gene regulation as a field has matured much during decades of study, but understanding it on a genome-wide basis has started in earnest only with the assembly of genomic data. Identifying genome-wide regulatory motifs is problematic due to their typically low consensus sequences; grasping which transcription factors bind to such motifs is even more difficult, as numerous factors can bind to any one motif. Nonetheless, with many diseases l...

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