Summary
In 2002 Wagers published evidence contrary to claims that bone marrow-derived stem cells could transdifferentiate into brain, muscle, and other tissues.1 In 2004, she found that hematopoietic stem cells could not repair damaged myocardium,2 despite other evidence that it could (Nature, 410:701-5, 2001). In 2007, for example, Piero Anversa at Harvard Medical School - whose 2001 findings with Donald Orlic at the National Heart Lung and Blood Institute Wagers had challenged in 2004 - showed "unequivocally" that bone marrow stem cells could transdifferentiate to cardiomyogenic cells (Proc Natl Acad Sci, 104:17783-8,2007).
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Extract
Amy Wagers: Setting the Record Straight
As a postdoc in Irving Weissman's laboratory at Stanford University, Amy Wagers earned a reputation for putting other people's findings to the test. In 2002 Wagers published evidence contrary...
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