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Scientist, The
Restoring Natural Capital
By infecting guinea pigs with a Shigella strain that expressed a mutant version of OspE that was unable to bind to the kinase and help cells form those focal adhesions, they protected these animals from the severe inflammation and diarrhea that would have afflicted them had they been infected with wild-type Shigella. F1000 Associate Faculty Member Melanie Hamon's lab researches how Listeria monocytogenes, another bacterium that infects the intestinal epithelium, affects host transcription an...